A 2022 Choice Reviews Outstanding Academic Title An important history of the development of cancer centers of excellence and the revolution in cancer treatment. In the 1960s a coalition of concerned citizens, scientists and politicians joined forces to convince the federal government to focus its efforts on conquering cancer. The National Cancer Act of 1971 resulted and was signed into law on December 23, 1971 by President Nixon. The national “War on Cancer,” was declared with some leaders naively arguing that the disease would be conquered by the nation’s bicentennial—a mere five years in the future. Over the next five decades scientific discoveries demonstrated the great complexity of what had formerly been thought of as a single disease – with the advent of the genetic characterization of cancers, it is now recognized that there are almost an infinite number of cancers as defined by their many genetic mutations. The National Cancer Act established the infrastructure for the designation of centers by the National Cancer Institute (NCI) and these centers have evolved into models of multidisciplinary, collaborative cancer research, treatment and prevention contributing to a reduction in cancer mortality and increase in quality of life and survival that has translated into more than 17 million cancer survivors in the United States in 2021. Centers of the Cancer Universe: A Half-Century of Progress Against Cancer tells the story of how cancer research was not front and center at most universities and research institutions before the National Cancer Act of 1971, and why many physicians were reluctant even to treat patients with cancer in the early 20th century. It follows the behind-the-scenes lobbying, resistance and negotiating that preceded signing the Act into law, and how the cancer centers of today came to fruition, and shaped how cancer research, clinical trials and treatment would be conducted.

LOS ANGELES TIMES BOOK PRIZE WINNER • An MIT astrophysicist reinvents herself in the wake of tragedy and discovers the power of connection on this planet, even as she searches our galaxy for another Earth, in this “bewitching” (Anthony Doerr, The New York Times Book Review) memoir. “Sara Seager’s exploration of outer and inner space makes for a stunningly original memoir.”—Abraham Verghese, author of Cutting for Stone Sara Seager has always been in love with the stars: so many lights in the sky, so much possibility. Now a pioneering planetary scientist, she searches for exoplanets—especially that distant, elusive world that sustains life. But with the unexpected death of Seager’s husband, the purpose of her own life becomes hard for her to see. Suddenly, at forty, she is a widow and the single mother of two young boys. For the first time, she feels alone in the universe. As she struggles to navigate her life after loss, Seager takes solace in the alien beauty of exoplanets and the technical challenges of exploration. At the same time, she discovers earthbound connections that feel every bit as wondrous, when strangers and loved ones alike reach out to her across the space of her grief. Among them are the Widows of Concord, a group of women offering advice on everything from home maintenance to dating, and her beloved sons, Max and Alex. Most unexpected of all, there is another kind of one-in-a-billion match, not in the stars but here at home. Probing and invigoratingly honest, The Smallest Lights in the Universe is its own kind of light in the dark.

Since the mid-1990s, an exciting building project has been underway: new cancer care centers that offer a new approach to architecture and health. Named after Maggie Keswick and cofounded with her husband, the writer and landscape designer Charles Jencks, these centers aim to be at all the major British hospitals that treat cancer. "The Architecture of Hope" showcases these structures where, under one roof, patients can access help with information, benefits, psychological support, and stress-reducing strategies. The book offers a history of the centers, as well as profiles of individual centers throughout the U.K. "The Architecture of Hope" is a testament to these places of hope and healing, available to anybody, whether or not they are afflicted with this terrible disease.

An unprecedented constellation of experts—leading cancer doctors, policymakers, cutting-edge researchers, national advocates, and more—explore the legacy and the shortcomings from the fifty-year war on cancer and look ahead to the future. The longest war in the modern era, longer than the Cold War, has been the war on cancer. Cancer is a complex, evasive enemy, and there was no quick victory in the fight against it. But the battle has been a monumental test of medical and scientific research and fundraising acumen, as well as a moral and ethical challenge to the entire system of medicine. In A New Deal for Cancer, some of today’s leading thinkers, activists, and medical visionaries describe the many successes in the long war and the ways in which our deeper failings as a society have held us back from a more complete success. Together they present an unrivaled and nearly complete map of the battlefield across dimensions of science, government, equity, business, the patient provider experience, and more, documenting our emerging understanding of cancer’s many unique dimensions and offering bold new plans to enable the American health care system to deliver progress and hope to all patients.

"The Higgs boson ... is the key to understanding why mass exists and how atoms are possible. After billions of dollars and decades of effort by more than six thousand researchers at the Large Hadron Collider in Switzerland--a doorway is opening into the mind-boggling world of dark matter and beyond. Caltech physicist and acclaimed writer Sean Carroll explains both the importance of the Higgs boson and the ultimately human story behind the greatest scientific achievement of our time"--Publisher

Atheism Made Easy is a guide to losing your faith! This contribution to the philosophy of religion is a scathing attack on irrational belief in a god or gods.

This enhanced eBook includes video, audio, photographic, and linked content, as well as a bonus short story. Hear TAMMY talk. Learn the origins of Minor Universe 31. See the TM-31. Take a trip in it. Photos and illustrations appear as hyperlinked endnotes. Video and audio are embedded directly in text. *Video and audio may not play on all readers. Check your user manual for details. National Book Foundation 5 Under 35 Award winner Charles Yu delivers his debut novel, a razor-sharp, ridiculously funny, and utterly touching story of a son searching for his father . . . through quantum space–time. Minor Universe 31 is a vast story-space on the outskirts of fiction, where paradox fluctuates like the stock market, lonely sexbots beckon failed protagonists, and time travel is serious business. Every day, people get into time machines and try to do the one thing they should never do: change the past. That’s where Charles Yu, time travel technician—part counselor, part gadget repair man—steps in. He helps save people from themselves. Literally. When he’s not taking client calls or consoling his boss, Phil, who could really use an upgrade, Yu visits his mother (stuck in a one-hour cycle of time, she makes dinner over and over and over) and searches for his father, who invented time travel and then vanished. Accompanied by TAMMY, an operating system with low self-esteem, and Ed, a nonexistent but ontologically valid dog, Yu sets out, and back, and beyond, in order to find the one day where he and his father can meet in memory. He learns that the key may be found in a book he got from his future self. It’s called How to Live Safely in a Science Fictional Universe, and he’s the author. And somewhere inside it is the information that could help him—in fact it may even save his life. Wildly new and adventurous, Yu’s debut is certain to send shock waves of wonder through literary space–time.