A comprehensive examination of this burgeoning area of important research.

Introductory textbook describing the ways in which bacteria cause disease at the molecular and cellular level.

This volume in the Methods in Microbiology series focuses on the interaction of microorganisms and the host cell, presenting detailed experimental techniques for modern microbiological research. The book focuses on current technical methods, including imaging technologies, cellular biochemistry, and the establishment and exploitation of cell assay systems. Also covered are methods for studying gene expression and detecting virulence genes. By studying the major techniques used to study cross talk between microbes and cells, rather than just presenting systems, this book distinguishes itself as an essential guide for all researchers working in microbiology, cell biology, and immunology. Key Features * Focuses on current technical methods, including imaging technologies, cellular biochemistry, establishment and exploitation of cell assay systems * Covers promising new areas such as global analysis of genome expression and proteomic analysis of cellular components. * Encompasses the most recent and innovative techniques such as microarrays, new experimental models of infection and new cell assay systems * Provides a large array of models covering the various strategies used by pathogens to infect their host * Includes all current methods developed to study gene expression and detect virulence genes.

Bacteriophages are viruses that infect bacteria; as such, they have many potential uses for promoting health and combating disease. This book covers the many facets of phage-bacterial-human interaction in three sections: the role and impact of phages on natural bacterial communities, the potential to develop phage-based therapeutics and other aspects in which phages can be used to combat disease, including bacterial detection, bacterial epidemiology, the tracing of fecal contamination of water and decontamination of foods.