The 1st International Conference On Culture, Education, Linguistics, and Literature (CELL) Universitas Jenderal Soedirman (Jenderal Soedirman University). The rapid development of information and communication technology on information continuously encourages the global society known as Industrial Revolution 4.0. It was first introduced by German Economist, Klaus Schwab, in his book entitled “The Fourth Industrial Technology” in 2012. The complexity and interconnected sector in our daily life urge all stakeholders of the global society (governments, business actors, academicians, and civil society) have the responsibility to work together. The conference invites delegates from across Indonesian and attended by more than 75 participants from university academics, researchers, practitioners, and professionals across a wide range of industries.

With the fascinating scholarship of The Emperor of All Maladies and the deeply personal experience of When Breath Becomes Air, a world-class oncologist examines the current state of cancer and its devastating impact on the individuals it affects -- including herself. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must. A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.

The field of cell biology is so vast and changing so rapidly that teaching it can be a daunting prospect. The first edition of The Cell: A Molecular Approach, published in 1997, offered the perfect solution for teachers and their students-current, comprehensive science combined with the readability and cohesiveness of a single- authored text. Designed for one-semester introductory cell biology courses, this book enabled students to master the material in the entire book, not simply to sample a small fraction from a much larger text. The new second edition of The Cell retains the organization, themes, and special features of the original, but has been completely updated in major areas of scientific progress, including genome analysis; chromatin and transcription; nuclear transport; protein sorting and trafficking; signal transduction; the cell cycle; and programmed cell death. With a clear focus on cell biology as an integrative theme, topics such as developmental biology, plant biology, the immune system, the nervous system, and muscle physiology are covered in their broader biological context. Each chapter includes a brief chapter outline, bold-faced key terms, and chapter-end questions with answers in the back of the book.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. - Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside - Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios - Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

This volume provides a comprehensive overview for investigating biology at the level of individual cells. Chapters are organized into eight parts detailing a single-cell lab, single cell DNA-seq, RNA-seq, single cell proteomic and epigenetic, single cell multi-omics, single cell screening, and single cell live imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Single Cell Methods: Sequencing and Proteomics aims to make each experiment easily reproducible in every lab.

This detailed book provides state-of-art computational approaches to further explore the exciting opportunities presented by single-cell technologies. Chapters each detail a computational toolbox aimed to overcome a specific challenge in single-cell analysis, such as data normalization, rare cell-type identification, and spatial transcriptomics analysis, all with a focus on hands-on implementation of computational methods for analyzing experimental data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Methods for Single-Cell Data Analysis aims to cover a wide range of tasks and serves as a vital handbook for single-cell data analysis.