Pragmatic Randomized Clinical Trials Using Primary Data Collection and Electronic Health Records addresses the practical aspects and challenges of the design, implementation and dissemination of pragmatic randomized trials. The book contains chapters encompassing common designs, along with the advantages and limitations of such designs, analytic aspects in planning trials and estimating sample size, and how to use patient partners to help design and operationalize such trials. Pragmatic trials conducted using primary data collection and trials embedded in electronic health records - including electronic medical records and administrative insurance claims - are addressed. This comprehensive resource is valuable not only for biostatitians, but also for several members of biomedical field who are interested in applying pragmatic randomized clinical trials in their research. Brings typical designs and challenges of pragmatic randomized clinical trials (pRCTs) Encompasses analytic aspects for sample size determination of such trials Discusses real cases on operational challenges in launching and conducting pRCTs in electronic health records

This definitive manual describes how to "prepare" a piano properly (for compositions by John Cage and other composers for prepared piano) without damaging the instrument. The book includes numerous photos, diagrams, drawings, "Checklist for a Basic Preparation Kit", "Where to Obtain Materials", an annotated list of compositions for prepared piano, etc. Second American Edition, revised and expanded. - Author website.

This is a richly illustrated history of the clavichord, the forerunner of the modern piano.