Unlock the secret to creating maximum business value from technology Filled with case studies from leading C-level executives to illustrate concepts discussed, Breakthrough IT is a revolutionary approach to reshaping the corporate information technology function. This innovative, step-by-step guide provides concrete methods every business can implement to yield maximum value and competitive advantage from their IT organization. Patrick Gray (Harrison, NY) is the founder and President of the Prevoyance Group, an IT strategy consultancy that combines project management and process improvement to ensure large IT departments deliver maximum organizational value.

Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

This is a *different* book on change management. Using commonsense and practical advice tested in their work with hundreds of organizations, the authors walk the reader through clear guidelines and checklists to implement change that works. Readers will develop a change management strategy that starts by diagnosing the current culture and organization, then prepares for change carefully, addresses resistance to change, develops the change strategy, measures results, builds momentum for further change, and prevents deterioration and reversion. The authors then apply their framework to two areas that are major targets for change management: implementing new technology and systems and implementing successful e-business strategies. Included throughout are real-world examples from a number of industries and government.

"Hang on and watch your life take flight with FlyGirl!" -Marcia Wieder, CEO and Founder of Dream University Before she was thirty years old, Vernice "FlyGirl" Armour had become a decorated naval aviator, Camp Pendleton's 2001 Female Athlete of the Year and Strongest Warrior winner, the first female African-American on Nashville's motorcycle police squad, and a member of the San Diego Sunfire professional women's football team. She's a force to be reckoned with, and she believes that women and men from all walks of life have the potential to achieve the highest levels of success with the right flight plan. In Zero to Breakthrough, Vernice turns aspiration into action by revealing how to create the path that will get you out of your rut on onto the runway - cleared for take off. Armour firmly believes that there is no such thing as a dream out of reach. Integrating the foundational concepts of a Breakthrough MentalityTM like preparation, strategy, courage, legacy, and the importance of high spirits and enthusiasm, Zero to Breakthrough helps readers build a sustainable inner force and conviction that result in accomplishing significant goals and becoming an extraordinary member of any business or community. Packed with hard-hitting advice and amazing anecdotes from her adventures on the battlefield and in business, you'll learn strategies like how to: *Stop procrastinating and prepare to lay the groundwork for success *Execute situations with self-discipline to achieve mastery *Acknowledge and move past obstacles & challenges *Feel fear and use it to keep charging, and much more Whether you want to jump up the corporate ladder, start your own business, or develop a passion into a livelihood, Zero to Breakthrough will get you there. For anyone seeking a more fulfilling life, Armour has the ultimate launch pad.

All of us struggle at one time or another with creative block. Always striking at the worst moment, it can leave you feeling completely paralyzed. Take solace in knowing that you are not alone. It happens to everyone and is actually an inevitable part of the creative process. Breakthrough!is a lively compilation of strategies for combating creative block offered by a who's who of leading graphic designers, typographers, cartoonists, photographers, illustrators, musicians, writers, and other creative professionals. Because every block is different, they offer a wide variety of solutions—from cleaning the house and eating spicy food to making a plaster cast of your hands and feet—that are surprising, amusing, at times weird, but always inspiring. Breakthrough! is rocket fuel for any creative individual in need of a catalyst to get ideas flowing again.

As the title suggests, Breakthrough! The Bible for Young Catholics highlights what happens throughout salvation history between God and humanity. God breaks through and connects with human history, thereby establishing a relationship with humanity. Using the Good News translation, Breakthrough! The Bible for Young Catholics was created for young people leaving childhood and entering adolescence. Its ten special features were created to help make the Bible easier for young people to read and understand. They will learn about the great people of the Bible, and will see how God has been breaking through in human history and connecting with humanity for thousands of years. Most important, they will discover, in the Bible, how God's messages to key people of faith have meaning for life today.

Exploring some of the ways in which repair practices and perceptions of brokenness vary culturally, Repair, Brokenness, Breakthrough argues that repair is both a process and also a consequence which is sought out—an attempt to extend the life of things as well as an answer to failures, gaps, wrongdoings, and leftovers. This volume develops an open-ended combination of empirical and theoretical questions including: What does it mean to claim that something is broken? At what point is something broken repairable? What are the social relationships that take place around repair? And how much tolerance for failure do our societies have?