Neuroscience Research in Short-duration Human Spaceflight encapsulates a groundbreaking neuroscience portfolio conducted during the Axiom Mission 2 in May 2023, offering an examination of the effects of short-duration orbital spaceflight on aspects of the human brain. Addressing limitations in existing literature, the research includes astronauts of diverse ages, genders, and ethnic backgrounds, broadening the understanding of the impact of spaceflight on human physiology. A significant aspect of the suite of studies is the validation of two novel devices providing unprecedented information about the pupillary light reflex and neuroimaging in microgravity: automated pupillometry and functional near-infrared spectroscopy. The portfolio extends to explore spaceflight-associated neuro-ocular syndrome, offering valuable contributions to the evolving field of space medicine. Furthermore, the research delves into the utilization of electroencephalography to monitor brain activity, acknowledging its potential in assessing cognitive health, stress levels, and mental workload in real time. Despite promising prospects, challenges in electroencephalography system adaptability within the International Space Station environment are highlighted, emphasizing the need for specialized design considerations. In addition, analysis is extended into the molecular biomarkers through minimally invasive blood monitoring. This book represents a pivotal advancement in space neuroscience, laying the foundation for safer space travel and fostering the development of monitoring tools crucial to observing adverse changes and potentially developing countermeasures that can aid in the establishment of a permanent human presence beyond Earth. - Offers in-depth coverage of the effects of spaceflight on human physiology and the brain - Includes novel data from astronauts on the Axiom Mission 2 - Includes a range of monitoring tools to assess neurological activity during and after spaceflight

This book offers an overview of neuroscience research performed in space since the observations made during the first manned space flights to the detailed scientific investigations currently being carried out onboard the International Space Station. This book is for the general scientific reader. Each project and the reason why it was done is described with illustrations, rationale and hypothesis, and a summary of results. Also, reference lists guide readers to the published papers from experiments. This book is a legacy of what we have learned on brain mechanisms and functions through research done in space, and a guide for what could be investigated in the future.

In Psychology and Human Performance in Space Programs: Research at the Frontier, leading space researchers from multiple fields of expertise summarize the recent growth of knowledge, the resulting tools and techniques, and the research still needed to protect humans in space. Making use of cutting-edge research and development related to composing, training, and supporting astronaut crews who will live and work together for future missions to Mars, this book examines the current practices of leaders in the field both at NASA and in academia. Presenting astronaut data alongside data from analogous extreme environments such as mission simulation habitats, this volume helpfully contrasts and compares to examine the lessons that can be learned from other approaches. Using the context of current International Space Station missions, the book discusses the influence of human factors and physiological health on individual and team job performance and social cohesion. With an overview of the physical and psychological hazards of space, and the challenges posed by conducting space-related applied psychology research, this volume uses the context of a long-duration Mars mission as a lens through which to discuss adaptation and resilience, technical and team training, technological advances related to working and living in space, and human interaction with onboard systems. Additionally, the book includes an essay from retired astronaut Clay Anderson on his experiences in space and thoughts on future missions to the moon and Mars. This first of two volumes will be of interest to professionals in the field of human factors and psychology at work, as well as academics examining human performance in extreme environments and aerospace.

This book consolidates the current knowledge of how short and long-duration spaceflight affects the anatomy and physiology of the central nervous system. It also incorporates the methodology and constraints of studying the central nervous system in space. Chapters detail advances in imaging techniques available to assess intracranial and intraocular pathology as well as translational medicine with an emphasis on brain cancer and neurodegenerative disease in spaceflight. Additionally, the book offers theoretical background information, tested laboratory protocols, and step-by-step methods for reproducible lab experiments to aid neuroscientists and neurobiologists in laboratory testing and experimentation. Spaceflight and the Central Nervous System is the first to comprehensively include all aspects of spaceflight-induced changes in the central nervous system. It is an invaluable resource for basic and clinical laboratory trainees and researchers in aerospace medicine and physiology or for those looking to gain specific knowledge in spaceflight neuroscience.