An authoritative, concise, how-to guide to the various brain stimulation treatments used in psychiatry.

This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.

As understanding evolves about how different brain regions are involved in carrying out everyday tasks -- and in causing brain diseases when they go awry -- this book describes a new technology that allows physicians to focally stimulate the brain in awake adults through a non-invasive procedure. Transcranial Magnetic Stimulation in Clinical Psychiatry is an accessible and authoritative review of TMS, a procedure that is showing promise as a treatment in several disorders. Its authors explain how the procedure works, then the latest findings in a wide range of situations -- notably in depression, but also in other conditions ranging from migraine to stroke recovery. This concise overview of TMS offers practical guidance for psychiatrists and other clinicians using it as a therapy, or referring their patients to have this done, as well as updating the field for neuroscientists and neurologists. It begins with background on the physics and safety of TMS, a guide for administering the procedure, and a review of basic neurophysiological studies with TMS, showing how it can be used to measure connectivity and excitability of the cerebral cortex. The heart of book is then devoted to its clinical applications, organized by disorder: Epilepsy, movement disorders, and pain -- describes the use of TMS in inducing and inhibiting seizures and investigating their pathophysiology; in treating Parkinson's disease; and in relieving pain through motor cortex stimulation Major depression -- provides a critical review of research in the most-studied clinical application of TMS in psychiatry, where it is used as a therapeutic intervention and a neurophysiological probe Mania -- explores the effectiveness of TMS in light of its ECT-like properties through a trial of right TMS vs. sham TMS Anxiety disorders -- reports on investigations on the uses of TMS in treating obsessive-compulsive disorder and posttraumatic stress disorder Schizophrenia -- reviews studies utilizing single- or paired-pulse TMS to assess cortical inhibition and those that explore effects of extended trains of repetitive TMS in altering symptoms A further chapter on TMS in brain imaging shows how integrating imaging and TMS allows one to better place the TMS coil, better understand TMS effects on the brain, and improve understanding of how the brain mediates behavior. With a concluding overview of prospects for the future of repetitive TMS, this volume offers a definitive look at this cutting-edge research and provides critical guidance on how and when clinicians might use TMS in their practice.

A comprehensive survey of the state of current practice, this new edition of Brain Stimulation Therapies for Clinicians provides thoroughly updated information on the growing list of electrical stimulation therapies now in use or under study, including electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS), deep brain stimulation (DBS), cortical stimulation (CS), and transcranial direct current stimulation (TDCS), as well as new coverage of promising treatments such as low intensity focused ultrasound pulsation (LIFUP) and temporal interference stimulation (TI). After a brief course on the fundamentals of electricity and a refresher on neuroanatomy, the text explores how electricity works within biological systems before progressing to the chapters on individual therapies, which cover the history and evolution of the treatment, the techniques involved, clinical indications, side effects, and an up-to-date review of the evidence base supporting its use. The book is designed to help the reader cut through the initially daunting "alphabet soup" (e.g., ECT, TMS) by providing a clear and straightforward analysis of the prevailing techniques -- an indispensable resource for both clinicians and patients seeking in-depth knowledge of these acronyms and methods. The book's noteworthy features are many: Refinements in treatment protocols since the last edition are discussed in detail. For example, the sections on ECT cover advances such as focal electrically administered seizure therapy (FEAST) and magnetic seizure therapy (MST), while the TMS chapter covers theta burst and recent approval for obsessive-compulsive disorder. The underlying science is addressed in the initial review of electricity and physics, information that is foundational to these treatment modalities, but that clinicians do not encounter in the medical school curriculum. The section also addresses the parameters for brain stimulation and how to determine the right dose. A separate chapter is devoted to low intensity focused ultrasound pulsations (LIFUP) and temporally interfering (TI) electric fields, emerging treatments that have the potential to noninvasively stimulate focal locations deep in the brain without surgery or the implantation of hardware. The section on using DBS for treatment-resistant Parkinson's disease (PD) is thorough, authoritative, and a boon to clinicians assessing the viability and efficacy of treatment options for their PD patients. The new edition retains the amusing, but always informative sidebars highlighting the history of brain experimentation and applications of brain stimulation techniques Written in a down-to-earth, accessible style by authors at the forefront of progress in the field, Brain Stimulation Therapies for Clinicians is a rigorous, evidence based review of clinical data that focuses on what we know, what we don't know, and the strength of the evidence.

Deep Brain Stimulation: A New Frontier in Psychiatry provides an overview of current developments and the future possibilities of deep brain stimulation for patients with therapy-refractory psychiatric disorders. The side-by-side presentation of clinical applications and animal research provides a truly translational approach. Also included is a special chapter on the ethical issues involved in deep brain stimulation in psychiatry. Deep brain stimulation of selected brain areas has been shown to result in a substantial improvement of symptoms and quality of life in patients suffering from obsessive-compulsive disorder, major depressive disorder and drug addiction. Although it is still an experimental therapy and the number of psychiatric patients that are treated is low, its effectiveness and safety makes deep brain stimulation the most promising therapy for treating other serious and life-threatening psychiatric conditions.

Chronic electrical stimulation of the brain has demonstrated excellent outcomes in patients with Parkinson’s disease and has recently also been applied to various other neurological diseases. This comprehensive, up-to-date textbook will meet the needs of all who wish to learn more about the application of deep brain stimulation and will provide a sound basis for safe and accurate surgery. The book comprises two main parts, the first of which presents relevant anatomical and functional background information on the basal ganglia, thalamus and other brain structures as well as on the mechanism of brain stimulation. The second part describes clinical studies on deep brain stimulation, covering results in a range of movement disorders and psychiatric diseases and also important aspects of instrumentation and technique. The authors are outstanding scientists and experts in the field from across the world.