The near future. A terrible battle against a parasitic virus called "Gastrea" has been fought...and lost. Humanity is cornered and lives in despair. Rentaro and Enju face constant danger in their work as a team of specialists working for the Tendo Civil Security Agency, one of several groups dedicated to fighting Gastrea. Enju is one of the "cursed children," who survived the virus and gained superhuman powers as a result. A crazed top-hat-wearing terrorist is on the loose, but Rentaro's got his hands full just dealing with his fellow civsec agents!

The monstrous mutants created by the Gastrea virus have driven humanity to the brink of extinction. The only thing keeping them out of Tokyo are the giant Monoliths that surround the city and the efforts of civil security officers like Rentaro and Enju. But when they accept a strange mission from the Ministry of Defense, they uncover a plot by Kagetane Hiruko that could end in the destruction of humanity!

The Akasaka Palace reception hall is playing host to a summit welcoming the leaders of Japan's five governmental Areas. The Seitenshi, host and head of Tokyo Area, greets her equivalents from Osaka, Sendai, Hakata, and Hokkaido, and few are willing to lend a sympathetic ear to her attempts at brokering peace. The conference falls into chaos, the Seitenshi shocked that someone leaked out a state secret. The fallout soon brings the two Areas down the path to all-out war with each other--just as the Seitenshi vanishes from the palace!

Humanity continues to fight for its right to a future. Rentaro's enemy is the sinister Kagetane Hiruko, but there's another threat-a gigantic Stage Five Gastrea that threatens to destroy everything Rentaro has worked to protect. Overwhelming odds demand unthinkable sacrifices, but sometimes even that may not be enough...

Rentaro is still a fugitive, running from the law for a murder he didn't commit. He and Hotaru are bruised, bleeding, and barely on speaking terms, but they're equally desperate to uncover the identity of Suibara's killer. However, Police Superintendent Hitsuma hasn't given up on pursuing Rentaro! With Hitsuma's impending marriage to heartbroken Kisara advancing closer and closer, will Rentaro clear his name and rescue her in time? And what does saving Kisara mean for their future?

With the chaos of the Third Kanto Battle subsiding, peace is finally returning to the Tendo Civil Security Agency, and Rentaro, Kisara, Enju, and Tina are taking full advantage of the quiet. But when an old friend from Rentaro's childhood reappears, their bright days turn suddenly dark--and Rentaro finds himself imprisoned for a senseless murder. He plans a desperate escape, but his enemies keep coming, and they are like nothing he's ever fought before...

One of the giant Monoliths that protects Tokyo Area from the virally superpowered Gastrea creatures has been destroyed. And right on schedule, the Stage Four Gastrea Aldebaran leads an invading army of the monsters into the city. The elite self-defense forces are sent to face them, and the terrible sounds of war echo across a newly christened battlefield--but soon a tense silence falls. What is it that appears before the eyes of Rentaro and his friends? The near-future thriller of post-apocalyptic survival continues!