Basic Molecular Protocols in Neuroscience: Tips, Tricks, and Pitfalls

Basic Molecular Protocols in Neuroscience: Tips, Tricks, and Pitfalls
Title Basic Molecular Protocols in Neuroscience: Tips, Tricks, and Pitfalls PDF eBook
Author John T. Corthell
Publisher Academic Press
Pages 125
Release 2014-04-16
Genre Science
ISBN 0128015276

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Basic Neuroscience Protocols: Tips, Tricks, and Pitfalls contains explanatory sections that describe the techniques and what each technique really tells the researcher on a scientific level. These explanations describe relevant controls, troubleshooting, and reaction components for some of the most widely used neuroscience protocols that remain difficult for many neuroscientists to implement successfully. Having this additional information will help researchers ensure that their experiments work the first time, and will also minimize the time spent working on a technique only to discover that the problem was them, and not their materials. - Describes techniques in very specific detail with step-by-step instructions, giving researchers in-depth understanding - Offers many details not present in other protocol books - Describes relevant controls for each technique and what those controls mean - Chapters include references (key articles, books, protocols) for additional study - Describes both the techniques and the habits necessary to get quality results, such as aseptic technique, aliquoting, and general laboratory rules

Family Iridoviridae Molecular and Ecological Studies of a Family Infecting Invertebrates and Ectothermic Vertebrates

Family Iridoviridae Molecular and Ecological Studies of a Family Infecting Invertebrates and Ectothermic Vertebrates
Title Family Iridoviridae Molecular and Ecological Studies of a Family Infecting Invertebrates and Ectothermic Vertebrates PDF eBook
Author V. Gregory Chinchar
Publisher MDPI
Pages 234
Release 2019-10-01
Genre Science
ISBN 3039215167

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Ranaviruses and other viruses within the family Iridoviridae, infect a wide range of ecologically and commercially important ectothermic vertebrates, i.e., bony fish, amphibians, and reptiles, and invertebrates, including agricultural and medical pests and cultured shrimp and crayfish, and are responsible for considerable morbidity and mortality. Understanding the impact of these various agents on diverse host species requires the combined efforts of ecologists, veterinarians, pathologists, comparative immunologists and molecular virologists. Unfortunately, investigators involved in these studies often work in discipline-specific silos that preclude interaction with others whose insights and approaches are required to comprehensively address problems related to ranavirus/iridovirus disease. Our intent here is to breakdown these silos and provide a forum where diverse researchers with a common interest in ranavirus/iridovirus biology can profitably interact. As a colleague once quipped, “Three people make a genius.” We are hoping to do something along those lines by presenting a collection of research articles dealing with issues of anti-viral immunity, identification of a potentially novel viral genus exemplified by erythrocytic necrosis virus, viral inhibition of innate immunity, identification of novel hosts for lymphocystivirus and invertebrate iridoviruses, and modelling studies of ranavirus transmission. Collectively these and others will exemplify the breadth of ongoing studies focused on this virus family.

Emerging Fungal Plant Pathogens

Emerging Fungal Plant Pathogens
Title Emerging Fungal Plant Pathogens PDF eBook
Author Samantha Chandranath Karunarathna
Publisher Frontiers Media SA
Pages 159
Release 2021-11-05
Genre Science
ISBN 2889715949

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Poly(ADP-Ribose) Polymerase

Poly(ADP-Ribose) Polymerase
Title Poly(ADP-Ribose) Polymerase PDF eBook
Author Alexei V. Tulin
Publisher Springer Nature
Pages 441
Release 2022-12-14
Genre Science
ISBN 1071628917

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This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as well as the use of animal models and PARP1 inhibitor design and testing, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Poly(ADP-Ribose) Polymerase: Methods and Protocols, Third Edition presents essential new and classical methods for studying the pADPr-pathway.

Fundamentals of Forensic Biology

Fundamentals of Forensic Biology
Title Fundamentals of Forensic Biology PDF eBook
Author Avinash Puri
Publisher Springer Nature
Pages 539
Release
Genre
ISBN 9819931614

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Detection, Diagnosis and Management of Soil-borne Phytopathogens

Detection, Diagnosis and Management of Soil-borne Phytopathogens
Title Detection, Diagnosis and Management of Soil-borne Phytopathogens PDF eBook
Author Udai B. Singh
Publisher Springer Nature
Pages 506
Release 2023-03-28
Genre Science
ISBN 9811983070

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This edited book provides an overview of omics technologies and methods for integration across multiple omics layers used in the plant disease diagnosis and developing management strategies. The book concentrates on the prevalence of soil-borne disease management in various important crops with use of different strategies, including host resistance and biological control etc. The special focus is on the resolving practical problems encountered after the resistance development in the pathogens against several chemical pesticides. Further, special attention is given to the emergence of new diseases or the re-emergence of old ones on several crops, and on the results and problems encountered by using microbial inoculants, biofumigation and other non-chemical control methods. This book has 18 contributory chapters from the eminent experts in the field of plant pathology, microbiology and biotechnology working on different aspects of soil-borne diseases of important agricultural crops. This edited volume is of interest and useful to researchers in plant pathology, agriculture sciences, plant genomics ecology, policy makers, also it is a valuable source of reference to the relevant researchers and students globally.

Immunotherapy for Gastrointestinal Malignancies

Immunotherapy for Gastrointestinal Malignancies
Title Immunotherapy for Gastrointestinal Malignancies PDF eBook
Author Ramakrishna Vadde
Publisher Springer Nature
Pages 257
Release 2021-01-31
Genre Medical
ISBN 9811564876

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This book reviews current immunotherapeutic strategies for gastrointestinal (GI) malignancies, including immune composition, immune checkpoint inhibitors, cell therapy, and peptide vaccines used to protect against esophageal, gastric, hepato-biliary, pancreatic and colorectal cancers. It also discusses the current challenges of using immunotherapy for the treatment of gastrointestinal malignancies. The book reviews highly sensitive and specific immunomarkers for the detection of GI malignancies, and examines therapeutic vaccines and the major cytokines involved in GI immunotherapy, as well as their basic biology and clinical applications. In closing, the book explores various aspects of computational biology for the detection and treatment of GI malignancies.