Automated Drug Delivery in Anesthesia provides a full review of available tools and methods on the drug delivery of anesthesia, bridging the gap between academic development, research and clinical practice. The book takes an interdisciplinary approach, pulling information about tools developed in other disciplines such as mathematics, physics, biology and system engineering and applying them to drug delivery. The book's authors discuss the missing element of complete regulatory loop of anesthesia: the sensor and model for pain pathway assessment. This is the only book which focuses specifically on the delivery of anesthesia. - Revisits the standard TCI anesthesia regulatory loop - Provides complementary measurement devices and protocols for hypnosis, analgesia and neuromuscular blockade (the three components for anesthesia) - Describes the link between existing and emerging tools

Automated Drug Delivery in Anesthesia provides a full review of available tools and methods on the drug delivery of anesthesia, bridging the gap between academic development, research and clinical practice. The book takes an interdisciplinary approach, pulling information about tools developed in other disciplines such as mathematics, physics, biology and system engineering and applying them to drug delivery. The book's authors discuss the missing element of complete regulatory loop of anesthesia: the sensor and model for pain pathway assessment. This is the only book which focuses specifically on the delivery of anesthesia.

This book records the presentations given at a workshop held in Bonn in May 1994. The aim of the meeting was to bring together scientists from various disciplines and clinicians to discuss within a group of experts the theoretical, medical, engineering, and regulatory aspects of automated control of therapeutic interventions in. anaesthesiology. The meeting was considered a continuation of a preceding work shop on "Quantitation, Modelling and Control in Anaesthesia" [1], which was held also in Bonn 10 years ago in May 1984. That workshop dealt with problems of how to quantitate concepts like anaesthetic depth, how to model anaesthetic drug disposition, how to link phar macokinetics and pharmacodynamics, and how to use such concepts for the control of anaesthetic drug delivery. With respect to these topics the current proceedings have simultaneously both a broadened and a narrowed perspective. It is broadened in so far as the topics of the workshop did not focus exclusively on anaesthetic drugs and the control of their delivery, but did also discuss anaesthesia machine monitoring and patients therapeutic monitoring as well as control of blood pressure and artificial ventilation. The proceedings have nar rowed the perspective insofar as they do not intensively discuss the processes of quantitation and modelling but presuppose them and give more room to control, especially automated control. During the past 10 years informatics has tremendously expanded its knowledge and methods applicable to control problems.

An Overview of TCI and TIVA was written by two pioneers in the field of targeted drug delivery in anesthesia. Despite its small size, this book is a rich source of information on the structure, function, and clinical applications of target-controlled infusion (TCI) systems. [...] The text has the appearance of class notes rather than a formal manual; however, this feature enhances the tutorial dynamics of the book and should attract individuals involved in learning such as anesthesia residents and specialists flirting with total intravenous anesthesia (TIVA).' - David O. Warner, editor of Anesthesiology. AUTHORS: Anthony Absolom is Professor of Anesthaesiology at the University of Groningen. Michel Struys is Professor on Anaesthesia at Ghent University and the Universal Medical Center Groningen and Director at the British Journal of Anaesthesia. 27 b/w images

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

"Medication errors are the most common of all medical errors and pose a tremendous emotional and physical cost to patients and economic burden to our health system. The most reliable estimates of medication error in anesthesia place the rate at 1-2 in every 10 administrations, or 1 in every anesthetic. Most of the errors are harmless but other wreak devastation. These errors are a failure to plan well, or to carry out a well-designed plan; less talked about but perhaps more important are routine violations of best practices. Errors arise through fast and slow thinking; violations arise from a myriad of causes. There is an extensive body of expert consensus on how to improve medication safety, starting with an institutional commitment to improving medication safety, and ending with an individual practitioner committing to doing the right thing every time. Technical solutions, pharmacy solutions, standardization, and a safety culture are major themes in medication safety. Despite knowledge of what would make us safer, economic costs, a perceived lack of urgency, human resistance to change all conspire to medication safety difficult to achieve. Low-income countries face particular challenges in medication safety. Despite these challenges, we must dedicate ourselves anew to this goal - our patients deserve no less"--

This is an introduction to the patient monitoring technologies that are used in today’s acute care environments, including the operating room, recovery room, emergency department, intensive care unit, and telemetry floor. To a significant extent, day-to-day medical decision-making relies on the information provided by these technologies, yet how they actually work is not always addressed during education and training. The editors and contributors are world-renowned experts who specialize in developing, refining, and testing the technology that makes modern-day clinical monitoring possible. Their aim in creating the book is to bridge the gap between clinical training and clinical practice with an easy to use and up-to-date guide. · How monitoring works in a variety of acute care settings · For any healthcare professional working in an acute care environment · How to apply theoretical knowledge to real patient situations · Hemodynamic, respiratory, neuro-, metabolic, and other forms of monitoring · Information technologies in the acute care setting · New and future technologies