Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. This first reference devoted to the topic covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the combined expertise of 20 research groups from academia and leading pharmaceutical companies, this is a must-have for every drug developer and medicinal chemist applying the powerful methods of chemogenomics to speed up the drug discovery process.

Above Misminay, the sky also is so divided by the alternation of the two axes of the Milky Way passing through the zenith. This mirror-image quadri-partition of terrestrial and celestial spheres is such that a point within one of the quarters of the earth is related to a point within the corresponding celestial quarter. The transition between the earth and the sky occurs at the horizon, where sacred mountains are related to topographic and celestial features. Based on fieldwork in Misminay, Peru, Gary Urton details a cosmology in which the Milky Way is central. This is the first study that provides a description and analysis of the astronomical and cosmological system in a contemporary community in the Americas. Separate chapters take up the sun, the moon, meteorological phenomena, the stars, and the planets. Star-to-star constellations, the "animal" dark-cloud constellations that cut through the Milky Way, and certain twilight- and midnight-zenith stars are analyzed in terms of their spatial and temporal integration within an indigenous cosmological framework. Urton breaks new ground by demonstrating the indigenous merging of such forms of "precise knowledge" as astronomy, meteorology, agriculture, and the correlation of astronomical and biological cycles within a single calendar system. More than sixty diagrams clarify this Quechua system of astronomy and relate it to more familiar principles of Western astronomy and cosmology.

Twenty chapters present the range of current research into the study of textiles and dress in classical antiquity, stressing the need for cross and inter-disciplinarity study in order to gain the fullest picture of surviving material. Issues addressed include: the importance of studying textiles to understand economy and landscape in the past; different types of embellishments of dress from weaving techniques to the (late introduction) of embroidery; the close links between the language of ancient mathematics and weaving; the relationships of iconography to the realities of clothed bodies including a paper on the ground breaking research on the polychromy of ancient statuary; dye recipes and methods of analysis; case studies of garments in Spanish, Viennese and Greek collections which discuss methods of analysis and conservation; analyses of textile tools from across the Mediterranean; discussions of trade and ethnicity to the workshop relations in Roman fulleries. Multiple aspects of the production of textiles and the social meaning of dress are included here to offer the reader an up-to-date account of the state of current research. The volume opens up the range of questions that can now be answered when looking at fragments of textiles and examining written and iconographic images of dressed individuals in a range of media. The volume is part of a pair together with Prehistoric, Ancient Near Eastern and Aegean Textiles and Dress: an interdisciplinary anthology edited by Mary Harlow, C_cile Michel and Marie-Louise Nosch

This book explores the diversity and complexity of embodied experiences of maternity, illustrating how maternal bodies are constructed through different social, cultural and economic networks, and through different places and spaces.