The text presents a logical arrangement. Section I contains a general treatment of the anthelmintics, an excellent summary of the helminths of man and domestic animals, and a discussion of the correlation between chemical composition of the drugs and their anthelmintic action. The subtitle of Section II is "Anthelmintics Acting on Parasites in the Gut." The particular drugs used in the treatment of the cestodes and the nematodes are here considered: Male Fern, Pelletierine, Carbon Tetrachloride, Chenopodium, Santonin, Thymol, Beta Naphthol, and numerous others, some of them even of slight or doubtful value. Certain proprietary preparations are also discussed. Section III deals with "Anthelmintics used against somatic parasitic infections," the various antimony preparations and emetine. The more important drugs receive extensive treatment. For example, Carbon Tetrachloride is presented in outline as follows: Historical and General, Chemistry, Impurities and Tests for them, Pharmacological Action, Toxicology, Dosage and Methods of Administration, Effectiveness, Uses in Animals, and the Combination of Carbon Tetrachloride and Chenopodium

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A search of the literature reveals few references to critical tests of anthelmintics for the removal of thorn-headed worms from swine. In spite of the considerable economic importance of this parasite little attention has apparently been paid to treatment.

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This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.

Antiparasitic drugs (ATH) are important tools widely used to maintain animal welfare. As parasites impart a great impact on animal health, these drugs are often essential for the expression of the full genetic potential of production. However, despite the initial success, after years of massive use of anthelminthic drugs , the increase in prevalence of resistant nematodes became a major problem. Anthelmintics are commonly used to treat parasitic worm infections not only in animals, but humans as well. Resistance to anthelmintics is thought to be present in several helminth species, yet it remains poorly studied. This books discusses topics such as the clinical pharmacology of anthelmintics; the uses in human and veterinary medicine; animal resistance to ATH; and the efficacy of Neem and Pawpaw products against Oesophahostomum spp infection in pigs.