Advancing Prion Science
Title | Advancing Prion Science PDF eBook |
Author | Institute of Medicine |
Publisher | National Academies Press |
Pages | 289 |
Release | 2004-04-04 |
Genre | Medical |
ISBN | 0309090601 |
In Advancing Prion Science, the Institute of Medicine's Committee on Transmissible Spongiform Encephalopathies Assessment of Relevant Science recommends priorities for research and investment to the Department of Defense's National Prion Research Program (NPRP). Transmissible spongiform encephalopathies (TSEs), also called prion diseases, are invariably fatal neurodegenerative infectious diseases that include bovine spongiform encephalopathy (commonly called mad cow disease), chronic wasting disease, scrapie, and Creutzfeldt-Jakob disease. To develop antemortem diagnostics or therapies for TSEs, the committee concludes that NPRP should invest in basic research specifically to elucidate the structural features of prions, the molecular mechanisms of prion replication, the mechanisms of TSE pathogenesis, and the physiological function of prions' normal cellular isoform. Advancing Prion Science provides the first comprehensive reference on present knowledge about all aspects of TSEsâ€"from basic science to the U.S. research infrastructure, from diagnostics to surveillance, and from prevention to treatment.
Advancing Prion Science
Title | Advancing Prion Science PDF eBook |
Author | Institute of Medicine |
Publisher | National Academies Press |
Pages | 125 |
Release | 2003-04-20 |
Genre | Medical |
ISBN | 0309087449 |
In Advancing Prion Science, the Institute of Medicine's Committee on Transmissible Spongiform Encephalopathies Assessment of Relevant Science recommends priorities for research and investment to the Department of Defense's National Prion Research Program (NPRP). Transmissible spongiform encephalopathies (TSEs), also called prion diseases, are invariably fatal neurodegenerative infectious diseases that include bovine spongiform encephalopathy (commonly called mad cow disease), chronic wasting disease, scrapie, and Creutzfeldt-Jakob disease. To develop antemortem diagnostics or therapies for TSEs, the committee concludes that NPRP should invest in basic research specifically to elucidate the structural features of prions, the molecular mechanisms of prion replication, the mechanisms of TSE pathogenesis, and the physiological function of prions' normal cellular isoform. Advancing Prion Science provides the first comprehensive reference on present knowledge about all aspects of TSEs' from basic science to the U.S. research infrastructure, from diagnostics to surveillance, and from prevention to treatment. This report summarizes the progress thus far.
Advancing Prion Science
Title | Advancing Prion Science PDF eBook |
Author | Institute of Medicine |
Publisher | National Academies Press |
Pages | 125 |
Release | 2003-03-20 |
Genre | Medical |
ISBN | 0309168597 |
In Advancing Prion Science, the Institute of Medicine's Committee on Transmissible Spongiform Encephalopathies Assessment of Relevant Science recommends priorities for research and investment to the Department of Defense's National Prion Research Program (NPRP). Transmissible spongiform encephalopathies (TSEs), also called prion diseases, are invariably fatal neurodegenerative infectious diseases that include bovine spongiform encephalopathy (commonly called mad cow disease), chronic wasting disease, scrapie, and Creutzfeldt-Jakob disease. To develop antemortem diagnostics or therapies for TSEs, the committee concludes that NPRP should invest in basic research specifically to elucidate the structural features of prions, the molecular mechanisms of prion replication, the mechanisms of TSE pathogenesis, and the physiological function of prions' normal cellular isoform. Advancing Prion Science provides the first comprehensive reference on present knowledge about all aspects of TSEs' from basic science to the U.S. research infrastructure, from diagnostics to surveillance, and from prevention to treatment. This report summarizes the progress thus far.
Fatal Flaws
Title | Fatal Flaws PDF eBook |
Author | Jay Ingram |
Publisher | Yale University Press |
Pages | 294 |
Release | 2013-03-19 |
Genre | Medical |
ISBN | 0300189893 |
DIVThe story of the revolutionary science that is unraveling the mysteries of mad cow and other fatal brain diseases/div
Madness and Memory
Title | Madness and Memory PDF eBook |
Author | Stanley B. Prusiner |
Publisher | Yale University Press |
Pages | 344 |
Release | 2014-04-29 |
Genre | Science |
ISBN | 0300191146 |
The author, a 1997 recipient of the Noble Prize in medicine, describes the years he spent researching and demonstrating how the infectious proteins known as prions were responsible for brain diseases and how his theory has now become widely accepted in the science establishment.
Prion Biology
Title | Prion Biology PDF eBook |
Author | Stanley B. Prusiner |
Publisher | |
Pages | 0 |
Release | 2017 |
Genre | Medical |
ISBN | 9781621820932 |
Prions are infectious proteins responsible for diseases such as Creutzfeldt-Jakob disease and "mad cow" disease. They are misfolded versions of normal proteins that replicate by converting their normal cellular counterparts into abnormal prion proteins that disrupt cell function and can be transmitted to other cells and individuals. This book examines our under-standing of their structure, biochemistry, and pathophysiology.
Prions
Title | Prions PDF eBook |
Author | Akikazu Sakudo |
Publisher | |
Pages | 160 |
Release | 2019-03-12 |
Genre | Science |
ISBN | 9781910190951 |
Essential reading for everyone working with prions from the PhD student to the experienced scientist.