Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. - Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies - Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. - Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

This edited compilation presents some of the latest advancements in the field of nanotechnology. Chapter One details the use of self-emulsifying drug delivery systems as a technique for improving drug solubility. Chapter Two describes a proposal for improving the efficiency of solar panels by harvesting heat energy as well as light energy. Chapter Three investigates the efficacy of a sensor composed of carbon nanotubes and other nanomaterials for detecting toxic phenolic compounds in the environment. Chapter Four studies the characteristics of a sensor prepared with low-dimensional metal oxide nanoparticles with a fast response towards Xanthine. Chapter Five compares different approaches to modeling of the kinetics of metal nanoparticles formation and analyzes how these methods could be improved. Chapter Six deals with the use of heavy metal oxide nanoparticles for unsafe bio-chemical detection. Chapter Seven summarizes the importance, properties and applications of carbon nanotubes as a potential superior adsorbent group. Lastly, Chapter Eight obtains the structural model of an electroelastic actuator for nanotechnology.

Advances in Nano-fertilizers and Nano-pesticides in Agriculture: A Smart Delivery System for Crop Improvement explores the use of nanotechnology for the controlled delivery of pesticides, herbicides and fertilizers that improve the safety of products while also increasing the efficiency of food production and decreased environmental pollution. The development of nanodevices such as smart delivery systems to target specific sites, as well as nanocarriers for chemical controlled release are currently important aspects in novel agriculture and require a strong foundation of understanding, not only the technology, but also the resulting impacts. - Fills key knowledge- gaps of bio-nanotechnology, how they interact with plant cells and their biological consequences - Focuses on agro-nanotechnology which can be utilized for developing healthy seeds - Explores the possibilities of macronutrient nano-based fertilizers

Nanoparticles in Catalysis Discover an essential overview of recent advances and trends in nanoparticle catalysis Catalysis in the presence of metal nanoparticles is an important and rapidly developing research field at the frontier of homogeneous and heterogeneous catalysis. In Nanoparticles in Catalysis, accomplished chemists and authors Karine Philippot and Alain Roucoux deliver a comprehensive guide to the key aspects of nanoparticle catalysis, ranging from synthesis, activation methodology, characterization, and theoretical modeling, to application in important catalytic reactions, like hydrogen production and biomass conversion. The book offers readers a review of modern and efficient tools for the synthesis of nanoparticles in solution or onto supports. It emphasizes the application of metal nanoparticles in important catalytic reactions and includes chapters on activation methodology and supported nanoclusters. Written by an international team of leading voices in the field, Nanoparticles in Catalysis is an indispensable resource for researchers and professionals in academia and industry alike. Readers will also benefit from the inclusion of: A thorough introduction to New Trends in the Design of Metal Nanoparticles and Derived Nanomaterials for Catalysis An exploration of Dynamic Catalysis and the Interface Between Molecular and Heterogeneous Catalysts A practical discussion of Metal Nanoparticles in Water: A Relevant Toolbox for Green Catalysis Organometallic Metal Nanoparticles for Catalysis A concise treatment of the opportunities and challenges of CO2 Hydrogenation to Oxygenated Chemicals Over Supported Nanoparticle Catalysts Perfect for catalytic, organic, inorganic, and physical chemists, Nanoparticles in Catalysis will also earn a place in the libraries of chemists working with organometallics and materials scientists seeking a one-stop resource with expert knowledge on the synthesis and characterization of nanoparticle catalysis.

Nanoparticles in Pharmacotherapy explores the most recent findings on how nanoparticles are used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. This book is a valuable resource of recent scientific progress that includes the most cutting-edge applications of nanoparticles in pharmacotherapy. It is ideal for researchers, medical doctors and those in academia.

Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. - Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view - Presents the recent progress related to nanotherapeutics in the oral cavity - Provides the recent progress in the field of biomedical nanoparticles

Nanotechnology is a multidisciplinary field and has achieved breakthroughs in bioengineering, molecular biology, diagnostics, and therapeutics. Nanotechnology is the study of the control of matter on an atomic and molecular scale. Generally nanotechnology deals with structures of the size 100 nanometers or smaller, and involves developing materials or devices within that size. Nanotechnology is very diverse, ranging from novel extensions of conventional device physics, to completely new approaches based upon molecular self-assembly, to developing new materials with dimensions on the nanoscale, even to speculation on whether we can directly control matter on the atomic scale. There has been much debate on the future of implications of nanotechnology. Nanotechnology has the potential to create many new materials and devices with wide-ranging applications, such as in medicine, electronics, and energy production. On the other hand, nanotechnology raises many of the same issues as with any introduction of new technology, including concerns about the toxicity and environmental impact of nanomaterials, and their potential effects on global economics, as well as speculation about various doomsday scenarios. These concerns have led to a debate among advocacy groups and governments on whether special regulation of nanotechnology is warranted. Advances in Nanotechnology, Volume 3 gathers the latest research from around the globe in this dynamic field.