Written by over seventy scientists and clinicians worldwide from China, USA, Germany, Canada, Japan and other countries, this monograph, with nearly 450 figures and tables, covers a wide range of advanced progress in acupuncture research, from experimental research to clinical applications. In addition to exploring the histopathological basis for acupuncture and mathematical simulation of acupoint response to stimulation, initiation and transduction of acupuncture signals and cellular mechanisms during acupuncture effects as well as chemical and physical characteristics of moxibustion on acupoints are broadly discussed. The topics also include novel data on acupuncture effect with advanced imaging techniques, a unique understanding of meridian-viscera correlation, specific interactions between meridians and neurosensory organs within the system of homeostatic regulation and the acupuncture-induced influences on autonomic function. Several chapters introduce specific approaches with dry needling, silver needling and stainless needling for certain diseases, such as myofascitis, supportive care for breast cancer and chemotherapy-induced peripheral neuropathy as well as perioperative care of surgical patients. Moreover, this book discusses recent research on acupuncture therapy and potential mechanisms for a number of severe and refractory neurological disorders, including hyperactivity of hypothalamic-pituitary-adrenal axis, orofacial pain, chronic pain, itch, multiple sclerosis, autism spectrum disorders, cerebral palsy, depressive disorders, Alzheimer’s disease and ischemic brain injury. The vast amount of information offered in this book provides a comprehensive perspective on advanced acupuncture research to not only acupuncturists, but also to neuroscientists, neurologists, and other clinicians. For medical students and graduate and undergraduate students majoring in biology, physiology and neuroscience, this book offers an advanced course in learning about the mechanism-driven advances in alternative and complementary medicine.

Sleep disorders encompass a range of conditions that can significantly impact overall health, safety, and quality of life. Symptoms of sleep disorders include excessive daytime sleepiness, irregular breathing or movements during sleep, disrupted sleep, and difficulty falling asleep. If these conditions are not promptly and effectively treated, patients often experience various physical and mental complications, such as psychiatric disorders, cardiovascular disease, stroke, type 2 diabetes, and obesity, leading to a decreased overall quality of life. Complementary and alternative therapy (CAT) presents a potential approach for the prevention and treatment of sleep disorders. It encompasses a range of management practices, including cognitive behavioral therapy, exercise, mindfulness, meditation, transcranial magnetic stimulation, yoga, herbal medicine, acupuncture, acupressure, Gua Sha, moxibustion, Qigong, Tai Chi, acupoint catgut embedding, acupotomy, nutritional supplements, and vitamin supplements. However, the adoption of CAT for sleep disorders in clinical practice faces numerous challenges due to a limited understanding of their mechanisms and clinical effects.

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Written by over 60 scientists and clincicians from the United States, mainland China, Germany, Australia, Japan, Sweden, Portugal and Hong Kong, Current Research in Acupuncture discusses recent advances in acupuncture research in a modern scientific language. The first 5 chapters investigate the basic mechanisms of acupuncture. Later chapters explore topics including acupuncture treatment and potential mechanisms for epilepsy, Parkinson’s diseases, neurodegenerative disorders such as Alzheimer’s disease, vascular cognitive impairment, aging, anxiety, polycystic ovary syndrome, pain, nerve root cervical spondylosis, stroke, imflamation, myocardial ischemia and other cardiovascular diseases. Following the translational and clinical discussions, 4 chapters present new prospects for acupuncture theories and applications. The final chapter comments on the pitfalls and problems of the previous studies and suggests direction for future research towards in-depth understanding of acupuncture, along with better application of acupuncture in modern medicine. Each chapter is written by one or more experts in the field. This unique book provides a broad perspective on the principles of acupuncture for acupuncture researchers and neuroscientists. The laboratory and clinical investigations of various acupoints and optimal conditions provide unique clues to acupuncturists for improved clinical efficacy. For a medical student, this book is a modern course in ancient Traditional Chinese Medicine, especially acupuncture. Ying Xia, the chief editor, is Professor and Vice-Chairman of the Department of Neurosurgery at The University of Texas Medical School in Houston, Texas, USA. Guanghong Ding is Professor in the Department of Mechanics and Engineering Science at Fudan University and Director of Shanghai Research Center for Acupuncture and Meridians, Shanghai, China. Gen-Cheng Wu is Professor of Neurobiology; Chairman, Department of Integrative Medicine and Neurobiology; Director, Institute of Acupuncture Research; and Director, WHO Collaborating Center for Traditional Medicine, at Shanghai Medical College of Fudan University, Shanghai, China.