Innovative and unique, the "AAA Spiral Guides Amsterdam" combines cutting-edge design, a market-tested approach, and the trustworthiness of the American Automobile Association. This pocket-sized guide has a special, lay-flat spiral binding and is full-color throughout; easily portable and designed for on-the-spot travel reference. Also contains a Magazine section with original, engaging articles and photographs that highlight Amsterdam's culture and history.

Anne Frank's diary is combined with memories from people who knew her to create this biography.

Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step

The Craft and Science of Coffee follows the coffee plant from its origins in East Africa to its current role as a global product that influences millions of lives though sustainable development, economics, and consumer desire.For most, coffee is a beloved beverage. However, for some it is also an object of scientifically study, and for others it is approached as a craft, both building on skills and experience. By combining the research and insights of the scientific community and expertise of the crafts people, this unique book brings readers into a sustained and inclusive conversation, one where academic and industrial thought leaders, coffee farmers, and baristas are quoted, each informing and enriching each other.This unusual approach guides the reader on a journey from coffee farmer to roaster, market analyst to barista, in a style that is both rigorous and experience based, universally relevant and personally engaging. From on-farming processes to consumer benefits, the reader is given a deeper appreciation and understanding of coffee's complexity and is invited to form their own educated opinions on the ever changing situation, including potential routes to further shape the coffee future in a responsible manner. - Presents a novel synthesis of coffee research and real-world experience that aids understanding, appreciation, and potential action - Includes contributions from a multitude of experts who address complex subjects with a conversational approach - Provides expert discourse on the coffee calue chain, from agricultural and production practices, sustainability, post-harvest processing, and quality aspects to the economic analysis of the consumer value proposition - Engages with the key challenges of future coffee production and potential solutions

Describes recent surgical techniques developed to improve prognosis in aortic diseases, and discusses recent interventional strategies such as endovascular stent-graft placement and non-surgical reconstruction of the aorta. Chapters deal with aortic dissection, aortic aneurysm, surgical treatment of aortic aneurysms and dissections, inherited disorders of the aorta, aortic trauma, aortitis, and etiology and pathology of aortic malformations. Each chapter is organized in a similar fashion, with information on demographic aspects, pathology, clinical presentation, and diagnostic and therapeutic approaches. Annotation copyrighted by Book News, Inc., Portland, OR