Social isolation and loneliness are serious yet underappreciated public health risks that affect a significant portion of the older adult population. Approximately one-quarter of community-dwelling Americans aged 65 and older are considered to be socially isolated, and a significant proportion of adults in the United States report feeling lonely. People who are 50 years of age or older are more likely to experience many of the risk factors that can cause or exacerbate social isolation or loneliness, such as living alone, the loss of family or friends, chronic illness, and sensory impairments. Over a life course, social isolation and loneliness may be episodic or chronic, depending upon an individual's circumstances and perceptions. A substantial body of evidence demonstrates that social isolation presents a major risk for premature mortality, comparable to other risk factors such as high blood pressure, smoking, or obesity. As older adults are particularly high-volume and high-frequency users of the health care system, there is an opportunity for health care professionals to identify, prevent, and mitigate the adverse health impacts of social isolation and loneliness in older adults. Social Isolation and Loneliness in Older Adults summarizes the evidence base and explores how social isolation and loneliness affect health and quality of life in adults aged 50 and older, particularly among low income, underserved, and vulnerable populations. This report makes recommendations specifically for clinical settings of health care to identify those who suffer the resultant negative health impacts of social isolation and loneliness and target interventions to improve their social conditions. Social Isolation and Loneliness in Older Adults considers clinical tools and methodologies, better education and training for the health care workforce, and dissemination and implementation that will be important for translating research into practice, especially as the evidence base for effective interventions continues to flourish.

Drawing on the work of the Roundtable on Evidence-Based Medicine, the 2007 IOM Annual Meeting assessed some of the rapidly occurring changes in health care related to new diagnostic and treatment tools, emerging genetic insights, the developments in information technology, and healthcare costs, and discussed the need for a stronger focus on evidence to ensure that the promise of scientific discovery and technological innovation is efficiently captured to provide the right care for the right patient at the right time. As new discoveries continue to expand the universe of medical interventions, treatments, and methods of care, the need for a more systematic approach to evidence development and application becomes increasingly critical. Without better information about the effectiveness of different treatment options, the resulting uncertainty can lead to the delivery of services that may be unnecessary, unproven, or even harmful. Improving the evidence-base for medicine holds great potential to increase the quality and efficiency of medical care. The Annual Meeting, held on October 8, 2007, brought together many of the nation's leading authorities on various aspects of the issues - both challenges and opportunities - to present their perspectives and engage in discussion with the IOM membership.

Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information

A better way to learn…a word-building and body systems approach! A true blend of words, art, and technology, Medical Terminology Systems and Medical Language Lab (MLL) work together to create an immersive, multimedia experience that tracks each student’s progress until they’ve mastered the language of medicine. An access code inside new, printed textbooks unlocks an ebook, as well as access to MLL. Or choose the all-digital Instant Access option, which includes the ebook and immediate access to MLL. See what students are saying about the 8th Edition… Amazing Textbook for Medical Terms class. “I love the format that each chapter begins with a review of the body system. If you are entering the medical/healthcare field and need to take a medical terminology class this is the best book because its thorough and easy to use.”—Zora, Online Reviewer LEARN—Build a solid foundation with the text Students begin by learning the parts of words—roots, combining forms, suffixes, and prefixes. Then, they use their understanding of word parts to learn medical terminology. Mnemonic devices and engaging, interactive exercises make word-building fun and easy, ensuring students retain the information they need for success. PRACTICE—Study smarter, not harder Based on proven language methodology, Medical Language Lab (MLL) guides students step by step from basic through advanced levels of proficiency to become confident medical language speakers. Students review what they’ve learned from the text and in class through activities and quizzes. ASSESS—Build mastery. Attain fluency. Students and their instructors can monitor their progress through every MLL lesson and assignment to identify the areas where they’re struggling. A Review section provides additional activities for remediation. The Student Lesson Gradebook identifies which lessons have been completed (or not completed) and the grade earned, while the Student Activity Gradebook details how each student performed on specific assignments and how long they took to complete each.

Basic Science and Systemic Disease, Part 3 of The Netter Collection of Medical Illustrations: Musculoskeletal System, 2nd Edition, provides a highly visual guide to this body system, from foundational basic science and anatomy to orthopaedics and rheumatology. This spectacularly illustrated volume in the masterwork known as the (CIBA) "Green Books" has been expanded and revised by Dr. Joseph Iannotti, Dr. Richard Parker, and other experts from the Cleveland Clinic to mirror the many exciting advances in musculoskeletal medicine and imaging - offering rich insights into embryology; physiology; metabolic disorders; congenital and development disorders; rheumatic diseases; tumors of musculoskeletal system; injury to musculoskeletal system; soft tissue infections; and fracture complications. - Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. - Get complete, integrated visual guidance on the musculoskeletal system with thorough, richly illustrated coverage. - Quickly understand complex topics thanks to a concise text-atlas format that provides a context bridge between primary and specialized medicine. - Clearly visualize how core concepts of anatomy, physiology, and other basic sciences correlate across disciplines. - Benefit from matchless Netter illustrations that offer precision, clarity, detail and realism as they provide a visual approach to the clinical presentation and care of the patient. - Gain a rich clinical view of embryology; physiology; metabolic disorders; congenital and development disorders; rheumatic diseases; tumors of musculoskeletal system; injury to musculoskeletal system; soft tissue infections; and fracture complications in one comprehensive volume, conveyed through beautiful illustrations as well as up-to-date radiologic and laparoscopic images. - Benefit from the expertise of Drs. Joseph Iannotti, Richard Parker, and esteemed colleagues from the Cleveland Clinic, who clarify and expand on the illustrated concepts. - Clearly see the connection between basic science and clinical practice with an integrated overview of normal structure and function as it relates to pathologic conditions. - See current clinical concepts in orthopaedics and rheumatology captured in classic Netter illustrations, as well as new illustrations created specifically for this volume by artist-physician Carlos Machado, MD, and others working in the Netter style.