The Most Comprehensive and Cutting-Edge Guide to Statistical Applications in Biomedical Research With the increasing use of biotechnology in medical research and the sophisticated advances in computing, it has become essential for practitioners in the biomedical sciences to be fully educated on the role statistics plays in ensuring the accurate analysis of research findings. Statistical Advances in the Biomedical Sciences explores the growing value of statistical knowledge in the management and comprehension of medical research and, more specifically, provides an accessible introduction to the contemporary methodologies used to understand complex problems in the four major areas of modern-day biomedical science: clinical trials, epidemiology, survival analysis, and bioinformatics. Composed of contributions from eminent researchers in the field, this volume discusses the application of statistical techniques to various aspects of modern medical research and illustrates how these methods ultimately prove to be an indispensable part of proper data collection and analysis. A structural uniformity is maintained across all chapters, each beginning with an introduction that discusses general concepts and the biomedical problem under focus and is followed by specific details on the associated methods, algorithms, and applications. In addition, each chapter provides a summary of the main ideas and offers a concluding remarks section that presents novel ideas, approaches, and challenges for future research. Complete with detailed references and insight on the future directions of biomedical research, Statistical Advances in the Biomedical Sciences provides vital statistical guidance to practitioners in the biomedical sciences while also introducing statisticians to new, multidisciplinary frontiers of application. This text is an excellent reference for graduate- and PhD-level courses in various areas of biostatistics and the medical sciences and also serves as a valuable tool for medical researchers, statisticians, public health professionals, and biostatisticians.

Solve business problems involving time-to-event and resulting probabilities by following the modeling tutorials in Business Survival Analysis Using SAS: An Introduction to Lifetime Probabilities, the first book to be published in the field of business survival analysis! Survival analysis is a challenge. Books applying to health sciences exist, but nothing about survival applications for business has been available until now. Written for analysts, forecasters, econometricians, and modelers who work in marketing or credit risk and have little SAS modeling experience, Business Survival Analysis Using SAS builds on a foundation of SAS code that works in any survival model and features numerous annotated graphs, coefficients, and statistics linked to real business situations and data sets. This guide also helps recent graduates who know the statistics but do not necessarily know how to apply them get up and running in their jobs. By example, it teaches the techniques while avoiding advanced theoretical underpinnings so that busy professionals can rapidly deliver a survival model to meet common business needs. From first principles, this book teaches survival analysis by highlighting its relevance to business cases. A pragmatic introduction to survival analysis models, it leads you through business examples that contextualize and motivate the statistical methods and SAS coding. Specifically, it illustrates how to build a time-to-next-purchase survival model in SAS Enterprise Miner, and it relates each step to the underlying statistics and to Base SAS and SAS/STAT software. Following the many examples-from data preparation to validation to scoring new customers-you will learn to develop and apply survival analysis techniques to scenarios faced by companies in the financial services, insurance, telecommunication, and marketing industries, including the following scenarios: Time-to-next-purchase for marketing Employer turnover for human resources Small business portfolio macroeconometric stress tests for banks International Financial Reporting Standard (IFRS 9) lifetime probability of default for banks and building societies "Churn," or attrition, models for the telecommunications and insurance industries

Quantile regression is gradually emerging as a unified statistical methodology for estimating models of conditional quantile functions. By complementing the exclusive focus of classical least squares regression on the conditional mean, quantile regression offers a systematic strategy for examining how covariates influence the location, scale and shape of the entire response distribution. This monograph is the first comprehensive treatment of the subject, encompassing models that are linear and nonlinear, parametric and nonparametric. The author has devoted more than 25 years of research to this topic. The methods in the analysis are illustrated with a variety of applications from economics, biology, ecology and finance. The treatment will find its core audiences in econometrics, statistics, and applied mathematics in addition to the disciplines cited above.