This volume provides a concise yet comprehensive overview of minimal residual disease (MRD) testing. The text reviews the history of MRD testing, MRD testing for acute lymphoblastic leukemia/lymphoma, molecular diagnostics for MRD analysis in hematopoietic malignancies, the use of "difference from normal" flow cytometry in monitoring AML response, ML-DS for measurable residual disease detection, and advancements in next generation sequencing for detecting MRD. Written by experts in the field, Minimal Residual Disease Testing: Current Innovations and Future Directions is a valuable resource for hematologists, oncologists, pathologists, and radiologists on the variety of technologies available to detect MRD and how best to integrate these platforms into clinical practice.

Writings by the conceptual artist Michael Asher—including notes, proposals, exhibition statements, and letters to curators and critics—most published here for the first time. The California conceptual artist Michael Asher (1943–2012) was known for rigorous site specificity and pioneering institutional critique. His decades of teaching at CalArts influenced generations of artists. Much of Asher's artistic practice was devoted to creating works that had no lasting material presence and often responded to the material, social, or ideological context of a situation. Because most of Asher's artworks have ceased to exist, his writings about them have special significance. Public Knowledge collects writings by Asher about his work—including preliminary notes and ideas, project proposals, exhibition statements, and letters to curators and critics—most of which have never been previously published. Asher gave few interviews, didn't write art criticism, and rarely published extensive accounts of his own work. Yet writing was central to his artistic practice, serving as a tool for working out ideas, negotiating institutional parameters, and describing thought processes. In these texts, he considers writing and documentation, discusses artistic practice, offers notes for gallery and museum talks, presents artist statements for exhibition-goers, describes individual works and their situational context, and reflects on teaching and art education. Among other things, Asher provides his definition of site specificity, addresses the function of art in public space, and analyzes the intersection of teaching art and institutional models of education. Readers will see an artist at work, formulating ethical and political strategies for making art in a situational world.

This book evaluates and suggests potentially critical improvements to causal set theory, one of the best-motivated approaches to the outstanding problems of fundamental physics. Spacetime structure is of central importance to physics beyond general relativity and the standard model. The causal metric hypothesis treats causal relations as the basis of this structure. The book develops the consequences of this hypothesis under the assumption of a fundamental scale, with smooth spacetime geometry viewed as emergent. This approach resembles causal set theory, but differs in important ways; for example, the relative viewpoint, emphasizing relations between pairs of events, and relationships between pairs of histories, is central. The book culminates in a dynamical law for quantum spacetime, derived via generalized path summation.

This book undertakes a critical reappraisal of Minimalism through an examination of three key painters: Robert Mangold, David Novros, and Jo Baer. By establishing their substantive engagements with Minimalist discourse, as well as their often overlooked artistic exchanges with their sculptor peers, it demonstrates that painting crucially informed the movement’s development, serving not only as an object of critique but also as a crucible for its most central tenets. It also poses broader disciplinary implications as it historicizes and challenges Minimalism’s "death of painting" critiques that have been so influential to theories of modernism and postmodernism in the visual arts.

From the founder of This Gathered Nest YouTube channel, an uplifting story of Angela Braniff's unusual path to becoming the mother to seven children through various methods of adoption and biological approaches, encouraging women and mothers to embrace the unique purpose that God has put in their lives. Angela’s love for life and her family radiates through everything she does. The Braniff household includes their two biological daughters, Kennedy, 12, and Shelby 10; Rosie, 7, who was adopted from China with Down syndrome; Noah, 7, adopted from Congo; Jonah 5, adopted domestically; and finally, Ivy and Amelia, their one year old twins who were adopted as embryos, and implanted in Angela, who gave birth to them. In fact, after the book was finished, they joyfully welcomed a new baby into their home, Benjamin, through adoption, making them now a family of ten! Love Without Borders shares Angela's relatable, humorous, and honest view of motherhood. Angela chronicles her journey to discover God’s purpose for her life. For years she walked the safe, expected path, until one day she could feel God calling her to boldly step out and follow him into new places, which led her to raise a large, non-traditional family that looked different than she ever imagined. It was a winding path to motherhood, complete with heartbreak from failed adoptions, challenging pregnancies, and secondary infertility, but through it all Angela found the unique adventure God had for her. She has shared her family’s stories on her popular YouTube channel, This Gathered Nest, and now invites us in to go deeper and listen to where God might be calling us to go and who we’ve been tasked with loving, no matter how unusual (or just plain crazy) it may sound! The beauty of God’s plan is he uses imperfect people to bring about perfectly beautiful stories.

NEW YORK TIMES BESTSELLER • The classic work that predicted the anxieties of a world upended by rapidly emerging technologies—and now provides a road map to solving many of our most pressing crises. “Explosive . . . brilliantly formulated.” —The Wall Street Journal Future Shock is the classic that changed our view of tomorrow. Its startling insights into accelerating change led a president to ask his advisers for a special report, inspired composers to write symphonies and rock music, gave a powerful new concept to social science, and added a phrase to our language. Published in over fifty countries, Future Shock is the most important study of change and adaptation in our time. In many ways, Future Shock is about the present. It is about what is happening today to people and groups who are overwhelmed by change. Change affects our products, communities, organizations—even our patterns of friendship and love. But Future Shock also illuminates the world of tomorrow by exploding countless clichés about today. It vividly describes the emerging global civilization: the rise of new businesses, subcultures, lifestyles, and human relationships—all of them temporary. Future Shock will intrigue, provoke, frighten, encourage, and, above all, change everyone who reads it.