The Progress in Brain Research series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Covers all key aspects of current research on 5-HT interaction with other neurotransmitters - Provides extensively referenced chapters, thus giving readers a comprehensive list of resources on topics covered - Includes comprehensive and in-depth background information written in a clear form that is accessible to both specialists and non-specialists

5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance, Part B, Volume 260 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Serotonin-noradrenalin interactions, Electrophysiological and neurochemical evidence for an interaction of serotonin on noradrenergic neurons, Serotonin and cannabinoid system, 5-HT/CB interaction in the CNS in health and disease, Serotonin2A receptors and Cannabinoids, CB1/5-HT/GABA in food intake, A close interaction between serotonergic system and BDNF in the mechanism of action of antidepressant, 5-HT/ Ach, Interaction of 5-HT2A/2C ligands and nicotine, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Progress in Brain Research series - Includes the latest information on the 5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance, Part B

This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson's disease. This extremely important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently active areas of dopamine/serotonin interactions. * Provides an understanding of the interaction between Serotonin and Dopamine. * Appeals equally to specialists, general practitioners, students and researchers. * Contributes to the debate on new pharmacological approaches to several psychopathological states * Gives a comprehensive anatomical description plus the physiology and pharmacology of dopaminergic and serotonergic systems * Singles out neuropsychiatric and suggests new therapeutic approaches.

This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson's disease. This extremely important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently active areas of dopamine/serotonin interactions. - Provides an understanding of the interaction between Serotonin and Dopamine - Appeals equally to specialists, general practitioners, students and researchers - Contributes to the debate on new pharmacological approaches to several psychopathological states - Gives a comprehensive anatomical description plus the physiology and pharmacology of dopaminergic and serotonergic systems - Singles out neuropsychiatric and suggests new therapeutic approaches

Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitters, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood, and pathological alterations in the serotonergic system underlie behaviour and psychiatric conditions (among a host of very successful drugs targeting the serotoninergic system are Prozac and Zoloft). This is the first truly integrated handbook providing a broad overview over the many face

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.