Additive manufacturing or 3D printing, manufacturing a product layer by layer, offers large design freedom and faster product development cycles, as well as low startup cost of production, on-demand production and local production. In principle, any product could be made by additive manufacturing. Even food and living organic cells can be printed. We can create, design and manufacture what we want at the location we want. 3D printing will create a revolution in manufacturing, a real paradigm change. 3D printing holds the promise to manufacture with less waste and energy. We can print metals, ceramics, sand, synthetic materials such as plastics, food or living cells. However, the production of plastics is nowadays based on fossil fuels. And that’s where we witness a paradigm change too. The production of these synthetic materials can be based also on biomaterials with biomass as feedstock. A wealth of new and innovative products are emerging when we combine these two paradigm changes: 3D printing and biomaterials. Moreover, the combination of 3D printing with biomaterials holds the promise to realize a truly sustainable and circular economy.

Additive manufacturing or 3D printing, manufacturing a product layer by layer, offers large design freedom and faster product development cycles, as well as low startup cost of production, on-demand production and local production. In principle, any product could be made by additive manufacturing. Even food and living organic cells can be printed. We can create, design and manufacture what we want at the location we want. 3D printing will create a revolution in manufacturing, a real paradigm change.3D printing holds the promise to manufacture with less waste and energy. We can print metals, ceramics, sand, synthetic materials such as plastics, food or living cells. However, the production of plastics is nowadays based on fossil fuels. And that's where we witness a paradigm change too. The production of these synthetic materials can be based also on biomaterials with biomass as feedstock.A wealth of new and innovative products are emerging when we combine these two paradigm changes: 3D printing and biomaterials. Moreover, the combination of 3D printing with biomaterials holds the promise to realize a truly sustainable and circular economy.

3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapters are written by field experts actively engaged in educational and research activities at the top universities in the world. The earlier chapters cover the fundamentals of 3D printing, including topics such as materials and hardware. The later chapters go on to cover innovative applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing - including 3D cell and organ printing and the role of AI - with a subsequent look at the applications of high-resolution printing, 3D printing in diagnostics, drug development, 4D printing, and much more. This updated new edition features completely revised content, with additional new chapters covering organs-on-chips, bioprinting regulations and standards, intellectual properties, and socio-ethical implications of organs-on-demand. Reviews a broad range of biomedical applications of 3D printing biomaterials and technologies Provides an interdisciplinary look at 3D printing in medicine, bridging the gap between engineering and clinical fields Includes completely updated content with additional new chapters, covering topics such as organs-on-chips, bioprinting regulations, intellectual properties, medical standards in 3D printing, and more

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient Explores the current generation of nanostructured 3D printed medical devices Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field. Discusses new possibilities in tissue engineering with 3D printing Presents a comprehensive coverage of the materials, techniques and tools needed for producing bioprinted tissues Reviews emerging technologies in addition to commercial techniques

Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine. Provides a new and versatile method to fabricating living tissue Discusses future applications for 3D bioprinting technologies, including use in the cardiac, skeletal, and nervous systems, and organ construction Describes current approaches and future challenges for translational science Runs the gamut of topics related to the subject, from hydrogels and polymers to nanotechnology, toxicity testing, and drug screening platforms

Rapid Prototyping of Biomaterials: Principles and Applications provides a comprehensive review of established and emerging rapid prototyping technologies (such as bioprinting) for medical applications. Rapid prototyping, also known as layer manufacturing, additive manufacturing, solid freeform fabrication, or 3D printing, can be used to create complex structures and devices for medical applications from solid, powder, or liquid precursors. Following a useful introduction, which provides an overview of the field, the book explores rapid prototyping of nanoscale biomaterials, biosensors, artificial organs, and prosthetic limbs. Further chapters consider the use of rapid prototyping technologies for the processing of viable cells, scaffolds, and tissues. With its distinguished editor and international team of renowned contributors, Rapid Prototyping of Biomaterials is a useful technical resource for scientists and researchers in the biomaterials and tissue regeneration industry, as well as in academia. Comprehensive review of established and emerging rapid prototyping technologies (such as bioprinting) for medical applications Chapters explore rapid prototyping of nanoscale biomaterials, biosensors, artificial organs, and prosthetic limbs Examines the use of rapid prototyping technologies for the processing of viable cells, scaffolds, and tissues