Written by physicians and surgeons, imaging specialists, and medical technology engineers, and edited by Dr. Evan M. Zahn of the renowned Cedars-Sinai Heart Institute, this concise, focused volume covers must-know information in this new and exciting field. Covering everything from the evolution of 3D modeling in cardiac disease to the various roles of 3D modeling in cardiology to cardiac holography and 3D bioprinting, 3-Dimensional Modeling in Cardiovascular Disease is a one-stop resource for physicians, cardiologists, radiologists, and engineers who work with patients, support care providers, and perform research. - Provides history and context for the use of 3D printing in cardiology settings, discusses how to use it to plan and evaluate treatment, explains how it can be used as an education resource, and explores its effectiveness with medical interventions. - Presents specific uses for 3D modeling of the heart, examines whether it improves outcomes, and explores 3D bioprinting. - Consolidates today's available information and guidance into a single, convenient resource.

3D Printing Applications in Cardiovascular Medicine addresses the rapidly growing field of additive fabrication within the medical field, in particular, focusing on cardiovascular medicine. To date, 3D printing of hearts and vascular systems has been largely reserved to anatomic reconstruction with no additional functionalities. However, 3D printing allows for functional, physiologic and bio-engineering of products to enhance diagnosis and treatment of cardiovascular disease. This book contains the state-of-the-art technologies and studies that demonstrate the utility of 3D printing for these purposes. - Addresses the novel technology and cardiac and vascular application of 3D printing - Features case studies and tips for applying 3D technology into clinical practice - Includes an accompanying website that provides 3D examples from cardiovascular clinicians, imagers, computer science and engineering experts

This book offers readers a comprehensive introduction to the techniques and application of 3D printing in cardiovascular medicine. To do so, it addresses the history, concepts, and methods of 3D printing, choice of printing materials for clinical purposes, personalized planning of cardiac surgery and transcatheter interventions with patient-specific models, enhancement of patient-physician communication, simulation of endovascular procedures, and advances in 3D bio-printing. The book particularly focuses on the application of 3D printing to improve the efficacy and safety of cardiac interventions, and to promote the realization of precision medical care. The book gathers contributions by an international team of experts in the field of cardiovascular medicine, who combine the latest findings with their own practical experience in using 3D printing to support the diagnosis and treatment of a wide range of cardiovascular diseases. They present in-depth discussions in the fields of congenital heart disease, valvular disease, coronary artery disease, cardiomyopathy, left atrial appendage occlusion, cardiac tumors and vascular diseases.

This book provides an overview of the use of rapid prototyping in patients with cardiac pathology. With the exponential increase in the use of prototyping, or 3D printing technology, medical applications are becoming more widespread across specialties. Although medical centers are beginning to apply this technology for improved patient care, there is no single text to which specialists can refer for guidance about this emerging modality. The book discusses the use of rapid prototyping in medicine; model creation; image acquisition; rapid prototyping techniques; applications in congenital and structural heart disease; and development and management of a rapid prototyping service. The use of rapid prototyping for pre-procedural planning in patients with cardiac disorders such as septal defects, Tetralogy of Fallot, transcatheter aortic valve replacement, and ventricular assist devices and heart transplant significantly enhances visualization of cardiovascular anatomy. Rapid Prototyping in Cardiac Disease is a unique and valuable resource for cardiac imaging specialists, cardiothoracic surgeons, radiologists, and biomedical engineers.

Since the publication of the second edition of this volume, 3D echocardiography has penetrated the clinical arena and become an indispensable tool for patient care. The previous edition, which was highly commended at the British Medical Book Awards, has been updated with recent publications and improved images. This third edition has added important new topics such as 3D Printing, Surgical and Transcatheter Management, Artificial Valves, and Infective Endocarditis. The book begins by describing the principles of 3D echocardiography, then proceeds to discuss its application to the imaging of • Left and Right Ventricle, Stress Echocardiography • Left Atrium, Hypertrophic Cardiomyopathy • Mitral Regurgitation with Surgical and Nonsurgical Procedures • Mitral Stenosis and Percutaneous Mitral Valvuloplasty • Aortic Stenosis with TAVI / TAVR • Aortic and Tricuspid Regurgitation • Adult Congenital Heart Disease, Aorta • Speckle Tracking, Cardiac Masses, Atrial Fibrillation KEY FEATURES In-depth clinical experiences of the use of 3D/2D echo by world experts Latest findings to demonstrate clinical values of 3D over 2D echo One-click view of 263 innovative videos and 352 high-resolution 3D/2D color images in a supplemental eBook.

The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

The availability of well-defined genetic strains and the ability to create transgenic and knockout mice makes mouse models extremely valuable biomedical tools. Their suitability as an experimental system for cardiovascular research depends on the individual investigator’s ability to manipulate the mice surgically. Many mouse models require microsurgical techniques, which hitherto could not be performed without practical training. This comprehensive handbook enables scientists to develop these models in their own laboratories. A Handbook of Mouse Models of Cardiovascular Disease is the first book to address pathology in mouse models of heart disease, providing the reader with essential information on technical assays in artificially created models. It includes background information on individual cardiovascular diseases, describes detailed methods and materials used for establishing each mouse model, discusses the problems that may appear in the experiments, and provides examples of applications of the model. A Handbook of Mouse Models of Cardiovascular Disease: Describes mouse models of all important cardiovascular diseases, including atherosclerosis, atrial fibrillation and thrombosis Features videos of key experimental procedures on the accompanying CD, allowing researchers to learn the techniques by directly watching the whole operational procedure Describes how to establish each experimental model with detailed protocols and tips on dealing with common operational problems Highlights potential applications of each model in areas such as pathogenesis, gene transfer, therapy and pathophysiology This handbook is an invaluable resource for researchers in cardiovascular disease, pathology, physiology, interested in the mechanism of vascular disorders and therapeutic approaches. It is also relevant to clinicians seeking to understand the pathology of cardiovascular disease and the rationale for interventions, and of interest to the pharmaceutical industry and all those involved in drug discovery/development for cardiovascular disease.