Examining the strengths and limitations of various standards of accuracy in clinical laboratory analyses, this detailed reference presents an in-depth study of important theoretical and empirical issues concerning the description, collection, and application of reference values in laboratory medicine.

Statistical Methods in Laboratory Medicine focuses on the application of statistics in laboratory medicine. The book first ponders on quantitative and random variables, exploratory data analysis (EDA), probability, and probability distributions. Discussions focus on negative binomial distribution, non-random distributions, binomial distribution, fitting the binomial model to sample data, conditional probability and statistical independence, rules of probability, and Bayes' theorem. The text then examines inference, regression, and measurement and control. Topics cover analytical goals for assay precision, estimating the error variance components, indirect structural assays, functional assays, bivariate regression model, and least-squares estimates of the functional relation parameters. The manuscript takes a look at assay method comparison studies, multivariate analysis, forecasting and control, and test interpretation. Concerns include time series structure and terminology, polynomial regression, assessing the performance of the classification rule, quantitative screening tests, sample correlation coefficient, and computer assisted diagnosis. The book is a dependable reference for medical experts and statisticians interested in the employment of statistics in laboratory medicine.

This text is designed for laboratory workers and clinicians but should also be useful for other healthcare workers. The authors assume that the reader has access to a computer with statistical software for inspection and analysis of data. The book has four main parts. Chapter 1 describes the different kinds of data and statistical analyses that can be applied to them. Topics include how to assess the shape of distributions, how to transform data, when to use parametric and non-parametric tests, and how to check data input and deal with outliers. Chapter 2 deals with the inaccuracy, imprecision, detection limits, analytical goals and other aspects of analytical methods used in laboratory medicine, and explains how to compare both quantitative and qualitative analytical methods.

The acclaimed full-color guide to selecting the correct laboratory test and interpreting the results –- covering ALL of clinical pathology A Doody’s Core Title for 2021! Laboratory Medicine is the most comprehensive, user-friendly, and well-illustrated guide available for learning how to order the correct laboratory test and understand the clinical significance of the results. The book features an easy-to-follow, consistent presentation for each disease discussed. Chapters begin with a brief description of the disorder followed by a discussion that includes tables detailing the laboratory evaluation of specific disorders, diagnosis, baseline tests to exclude diagnostic possibilities, and clinical indications that warrant further screening and special testing. With new, increasingly expensive and complicated tests appearing almost daily, Laboratory Medicine, Third Edition is required reading for medical students, clinical laboratory scientists, and healthcare professionals who want to keep abreast of the latest testing procedures and maximize accuracy and patient safety. Features: 48 clinical laboratory methods presented in easy-to-understand illustrations that include information on the expense and complexity of the assays More than 200 tables and full-color algorithms that encapsulate important information and facilitate understanding Full-color blood-smear micrographs that demonstrate common abnormal morphologies of red blood cells Valuable learning aids in each chapter, including learning objectives, chapter outlines, and a general introduction -- and new to this edition: chapter-ending self-assessment Q&A Logical systems-based organization that complements most textbooks Extensive table of Clinical Laboratory Reference Values that show the conversions between U.S. and SI units for each value

Pediatric Reference Intervals, Eighth Edition, is a must-have for clinical chemists, hematologists, pathologists, endocrinologists and pediatricians. This trusted source enhances interpretation of patient results, allows comparison of test results using different methods, and helps optimize patient care. This updated edition is a valuable reference, providing instant and accurate reference intervals for over 250 chemistry and hematology analytes in an alphabetized, user-friendly format. Changes to this edition include Age- and Sex-Related Reference Ranges, Methodologies, Type of Specimen, References, Statistical Basis and Population Sources. Provides the reference intervals for a wide variety of analytes for children, from neonates to adolescents to young adults Enhances interpretation of patient results, allows comparison of text results using different methods, and helps optimize patient care Trusted, vetted source that’s been in the market for decades