OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 15 |
Release | 2018-06-27 |
Genre | |
ISBN | 9264071180 |
The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 20 |
Release | 2018-06-27 |
Genre | |
ISBN | 9264071229 |
The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 18 |
Release | 2018-06-27 |
Genre | |
ISBN | 9264071202 |
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 4 |
Release | 1986-10-23 |
Genre | |
ISBN | 9264071482 |
The mouse spot test detects presumed somatic mutations in fetal cells following transplacental absorption of the test substance. This is an in vivo test in mice in which developing embryos are exposed to a chemical (solid, liquid, vapour or ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 20 |
Release | 2009-09-08 |
Genre | |
ISBN | 9264070605 |
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 14 |
Release | 2018-06-27 |
Genre | |
ISBN | 9264070826 |
This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method
Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method PDF eBook |
Author | OECD |
Publisher | OECD Publishing |
Pages | 14 |
Release | 2002-02-08 |
Genre | |
ISBN | 9264071008 |
This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.